The Spectra 5-Way Protection Vaccine is the ideal first shot for puppies. It is a combination of immunogenic, attenuated strains of Canine Distemper, Canine Adenovirus Type 2 (CAV-2), Canine Parainfluenza, and Canine Parvovirus Type 2b, propagated in cell line tissue cultures. The CAV-2 fraction cross-protects against respiratory infection caused by infectious canine hepatitis (CAV-1). Each dose comes with a syringe.